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C.Astorga-EloM.RenganathanP

As a result, little or no insulin is produced, and lifelong insulin therapy is essential (Malik 2014

Frontiers in physiology , 6 , 397

In comparison, fibrosis results in an overproduction of collagen over wider areas, hardening the tissue and making it less pliable

Other established ED treatments include: Vacuum erection devices Intracavernosal injections (alprostadil) Intraurethral alprostadil Testosterone replacement (for confirmed hypogonadism) Psychosexual therapy Penile prosthesis surgery (for refractory cases) All of these options have defined roles in ED management and are supported by clinical evidence

Afamelanotide melanocortin MC1 receptor agonist photoprotective agent
