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That is, once the treatment has stopped, patients vary widely in how quickly they weaken their colonisation and how long they may remain colonised (76).A heterogeneous distribution of gut bacteria throughout the gastrointestinal tract creates a significant risk that modified bacteria will not be able to effectively colonise their preferred area (77, 78)

Sun Y, He Y, Tong J, Liu D, Zhang H, He T, Bi Y (2022) All-trans retinoic acid inhibits the malignant behaviors of hepatocarcinoma cells by regulating ferroptosis

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