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Wani et al., 2023)

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It has been divided into three distinct phases: the initiation, the promotion or the proliferation step, and the termination

*Journal of Physiology and Pharmacology*, 64(6), 737-745

the lactate dyscrasia theory) proposes that mitochondrial dysfunction partly contributes to an accumulation of lactate in the junction of motor neurons and muscle cells (the neuromuscular junction (NMJ)) leading to death of both the nerve and muscle cells, thereby requiring the remaining muscle cells to work harder-than-normal to generate the force necessary for motor control

doi: 10.1038/s41598-018-37670-9 199 AlbalawiAEKhalafAKAlyousifMSAlanaziADBaharvandPShakibaieMet al
