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A ROS-responsive simvastatin nano-prodrug and its fibronectin-targeted co-delivery system for atherosclerosis treatment

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With the treatment time as the horizontal coordinate, the tumor volume and the mouse body weight as the vertical coordinate, the tumor growth curve and the mouse body weight change curve were plotted respectively

b Relative levels of PPP intermediates 6PG, ribulose-5-phosphate, S7P, and glycolytic intermediates: FBP, DHAP, and lactate 30 minutes after 100 nM PMA stimulation, with or without the treatment of G6PDi (50 M) or DPI (10 M)

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