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Biological subtypes of breast cancer: Prognostic and therapeutic implications

Modified oxidative lipid metabolism and dysregulated iron homeostasis have been implicated in the pathogenesis of this disorder, but the detailed pathophysiological mechanisms still remain unclear

Non-significant paths and non-significant indicators are deleted from the model

Mass spectrometric detection was carried out on a timsTOF Pro instrument (Bruker Daltonics) operating in positive ionization mode with trapped ion mobility spectrometry (TIMS) active at full duty cycle

Reduced glutathione and placebo were given for 120 days in a randomized double-blind fashion and the following measurements were performed: red blood cells reduced and oxidized glutathione, plasma reduced and oxidized glutathione, hematocrit, hemoglobin, reticulocytes, serum iron, transferrin, indirect bilirubin, urea, creatinine, calcium, phosphate, parathyroid hormone and alkaline phosphatase

Type II alveolar epithelial cells and interstitial fibroblasts express connective tissue growth factor in IPF