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Description
What does science say about it
Declining NAD[+] induces a pseudohypoxic state disrupting nuclear-mitochondrial communication during aging
Its very important for those with a severe deficiency
Then, patients move to monthly maintenance doses to keep B12 levels steady over time
[DOI] [PubMed] [Google Scholar] 72.Escande C, et al
The mechanism involves NAD+-dependent enzymes critical for glucose metabolism
