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n = 4) and the respective protein levels (PGC1) were assessed ( F

When the annulus tears or weakens, the nucleus can bulge or herniate, potentially compressing spinal nerves

Interestingly, the incubation with the antioxidant N-acetylcysteine (NAC) upon treatment with NP4 resulted in reduced levels of apoptosis, suggestive that the cytotoxicity of NP4 is related to intracellular redox homeostasis (Supplementary Fig

Electrophysiology results Based on a well-known phenomenon in peripheral nerve injury (i.e., as the number of preserved motoneurons decreases, the MUP (giant potential) in the tail muscle increases), it is conceivable that the BPC 157-treated rats that underwent spinal cord injury and were subjected to EMG recordings exhibited a markedly lower MUP in the tail muscle than that in the corresponding controls (Table 3)

Dick P, Grandjean ME, Tissot R

A sore, swollen, or unusually pale tongue can also be a tell-tale sign