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Short cell-penetration peptide conjugated bioreducible polymer enhances gene editing of CRISPR system

Nrf2 activation attenuates the early suppression of mitochondrial respiration due to the -synuclein overexpression

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Further, for poorly water-soluble drugs and biopharmaceuticals, such as proteins and peptides, powder formulations facilitate the formulation of larger drug doses by co-formulating using excipients that act as bulking agents (water-soluble fillers: lactose, trehalose, mannitol, and sorbitol

Therefore, hepatocytes in the centrilobular area produce more NAPQI and deplete GSH faster than cells in the periportal area 25,26