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Accordingly, the incidence of CIPN approaches nearly 100% for some agents at higher doses (Seretny et al., 2014), although differences in the definition, evaluation and reporting of peripheral neuronal deficits can lead to large variability in the reported occurrence

Clinical trials often include highly selected patients with strict entry criteria, prolonged illness duration, or extensive prior treatment

[16] method was used with little modifications

[DOI] [PubMed] [Google Scholar] 361

We tested whether acute depletion of glutathione can initiate ferroptosis in adult C

These findings suggest that activation of glutamine metabolism plays a role in protecting AML cells after iCT treatment, and suggest the potential application value of controlling glutamine metabolism to continuously eliminate AML cells