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Engaging underserved populations in trials : to ensure global applicability of therapies and biomarkers

Although NOX2 has been shown to enhance the pathogenesis in IAV infection through endosomal NOX2 oxidase-dependent ROS production, NOX4 oxidase exerts a protective effect against IAV infection 72
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[DOI] [PMC free article] [PubMed] [Google Scholar] 22.Wang X, Ma Y, Niu X, Su T, Huang X, Lu F, Chang Q

[DOI] [PMC free article] [PubMed] [Google Scholar] 828.Murphy, J

Elevated DKK1 levels in the bloodstream and bone microenvironment have been linked to enhanced cancer development through the modulation of -catenin levels in MDSCs, which can inhibit their immunosuppressive functions and support tumor growth [163]
