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Description
Recently, Benkoucha et al

Corrigan J

However, to date, oligonucleotide therapeutics are still facing some technological obstacles, such as how to achieve efficient oligonucleotide delivery to target organs or tissues, how to overcome off-target interactions [4952], and how to address the sequence- and chemistry-dependent toxicity and saturation of endogenous RNA processing pathways [53, 54]

A 2021 Nature Aging study by Lee and colleagues examined MOTS-c in the context of aging directly

There is no published human study confirming that SC DSIP produces equivalent blood levels to IV DSIP at the same nominal dose

Mayer A
