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The Role of Melanin in Skin Pigmentation Melanin serves as the body's natural defense mechanism against harmful ultraviolet radiation, but when melanin production becomes dysregulated, it leads to visible pigmentation problems

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In the elderly, even mild heat exposure increases wakefulness and decreases REM [55]

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The study identifies how deficiency of the 2-oxoglutarate carrier (Slc25a11) can trigger harmful changes in retinal pigment epithelial (RPE) cellsaccelerating subretinal fibrosis, a major cause of vision loss in neovascular age-related macular degeneration (AMD)

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