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This relationship has also shown that GSH depletion impairs dendritic cell mediated T-cell activation, further hindering immune response ( The glutaredoxin (Grx) system, another key player, operates in close association with the GSH pool and serves primarily to regulate protein thiol redox status through reversible de-glutathionylation

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Writing: EC, DB, JAS, MNM, AZ, BA, and MT wrote the manuscript

The results also showed that hypoxia for 4 h significantly increased the mortality of the primary neurons (Supplemental Fig