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This anti-angiogenic factor is capable of inhibiting endothelial cell proliferation, migration, and tube formation

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Ind Eng Chem Res 45:73517361, 2006

Itch: epidemiology, clinical presentation, and diagnostic workup

103 Furthermore, the EGFR and ERK pathways induce p-gp expression by activating PI3K signaling, while TGF-1 enhances P-gp through the HOTAIR/miR-145 axis, providing a novel mechanism for drug resistance in cancer
