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[11] Muscle weakness, the third manifestation of the disease, may accompany the heart failure or present by itself

Statistically, in healthy individuals, about 12 h after ED ingestion, there is an increase in systolic blood pressure by 610 mmHg, diastolic blood pressure by 36 mmHg, heart rate by about 37 beats/minute, and QT interval prolongation up to 2225 ms
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