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Therapeutic Approaches for Protecting the BBB by Inhibiting Oxidative Damage Antioxidants play a crucial role in protecting BBB integrity by counteracting the damaging effects of oxidative stress [143,196,205]

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Curcumin reduced the expression of inflammatory cytokines IL-1 and TNF, vascular cell adhesion molecule-1 (VCAM-1) an important cell adhesion molecule involved in inflammation and inflammatory leukotrienes and prostaglandins (Lamanna-Rama et al

Sibutramine is a prescription-only weight-loss medicine that has been banned in Singapore since 2010 due to an increased risk of heart attack and stroke

10.1016/j.brainres.2005.05.057 32

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