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doi: 10.1021/acssuschemeng.4c08602 [DOI] [Google Scholar] 78

Lawrence, R

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This figure illustrates all the important keys of how a molecular cascade is triggered, starting with increased melanocyte susceptibility to oxidative stress, which, in the presence of a susceptible genetic basis, leads to immune system activation

Acetaldehyde harms liver cell structure and function, causing: Decreased metabolism of amino acids and synthesis of many proteins (such as hemoglobin and red blood cells) Dysregulated gluconeogenesis and ketogenesis, and increased fat storage51 Dysregulated hormonal and energy homeostasis Accelerated red blood cell (RBC) destruction, elevating reactive oxygen species (ROS), altering metabolic pathways, damaging cells in various organs, and increasing AST and ALT levels

increased lung damage