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Phytochemistry 24 , 889896 (1985)

Travelers brought dried sorghum grains to parts of the Arabian Peninsula, India and China along the Silk Road

Abbreviations 11KT: 11-Ketotestosterone AKR1C3: Aldo-keto reductase family 1 member C3 CEBP: CCAAT-enhancer-binding protein- DHT: 5-Dihydrotestosterone E1: Oestrone E2: 17-Oestradiol HNF4: Hepatocyte nuclear factor 4 MASLD: Metabolic dysfunction-associated steatosis liver disease PCOS: Polycystic ovary syndrome PI3K: Phosphoinositide-3 kinase PPAR: Peroxisome proliferator-activated receptor SAT: Subcutaneous adipose tissue SHBG: Sex hormone-binding globulin VAT: Visceral adipose tissue WAT: White adipose tissue References Tramunt B, Smati S, Grandgeorge N et al (2020) Sex differences in metabolic regulation and diabetes susceptibility

Tricyclic Antidepressants Tricyclic antidepressants such as amitriptyline and nortriptyline have also been successful in the treatment of CVS

Fedele, D