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10.1016/j.neuropharm.2015.05.004 [DOI] [PubMed] [Google Scholar] Schwartz J

Furthermore, individual variability, conditioned by genetic and environmental factors, reinforces the need for personalized approaches to antioxidant supplementation to optimize its therapeutic potential

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Although NOX2 has been shown to enhance the pathogenesis in IAV infection through endosomal NOX2 oxidase-dependent ROS production, NOX4 oxidase exerts a protective effect against IAV infection 72

Am J Physiol Lung Cell Mol Physiol 299(3):L425-433

In particular, reactive oxygen species can differentially oxidize certain cysteine residues in target proteins and the reversible process of S-glutathionylation may mitigate or mediate the damage