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Chem Biol Interact 200:2127 Kudugunti SK, Vad NM, Ekogbo E, Moridani MY (2011) Efficacy of caffeic acid phenethyl ester (CAPE) in skin B16-F0 melanoma tumor bearing C57BL/6 mice
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As an important group of antioxidative enzymes, the normal levels of GPxs help to control the level of reactive species
Applications are strictly limited to experimental pathway analysis, not therapeutic use
An alternate pathway exists wherein resident macrophages initially clear small urate microaggregates (UMAs) formed due to HUA
