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In the presence of zinc deficiency, the activation of JNK and p38 MAPKs may be altered, leading to abnormal regulation of stress response genes and potential effects on apoptosis and inflammatory responses

The key role of astrocytes in amyotrophic lateral sclerosis and their commitment to glutamate excitotoxicity

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[DOI] [PMC free article] [PubMed] [Google Scholar] 9.Liu T, Sun W, Guo S, et al

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When -oxidation is limited, tumors avoid ferroptosis by (i) reducing PUFA incorporation into membranes 346 , (ii) deploying extramitochondrial ubiquinol recycling to trap lipid radicals 347,348 , and (iii) using the mitochondrial dihydroorotate dehydrogenase-ubiquinone axis to detoxify lipid peroxides in the inner membrane 349