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To account for the fact that glutathione mutants had shorter roots on the control plates, ratios between the average root length on each AITC concentration and on control medium are shown in Supplementary Figure S1

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When mitochondrial iron homeostasis is disrupted, cellular iron trafficking becomes dysregulated, leading to impaired energy metabolism, excessive ROS formation, and increased vulnerability to ferroptosis (62)

A mechanistic study showed that 1.25% BRS increased proliferation and reduced reactive oxygen species (ROS) generation and 5-reductase expression in hDPCs in vitro , findings comparable to those of minoxidil [136]