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This oxidative burden damages neuronal membranes and mitochondrial DNA, impairing energy supply and synaptic plasticity (113)

The results revealed no significant differences in the proportion of apoptotic SC- cells between the control and high-glucose groups or between the high-glucose-only group and the group treated with both high glucose and excess zinc (Supplementary information, Fig

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It aids in water retention, giving the skin a plump and hydrated appearance

As NRF2 transcriptional activity diminishes with age, the cells ability to mount an appropriate defense against baseline non-radical ROS such as H 2 O 2 , is compromised [8]

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