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Standard washout periods range from 46 weeks after an 812 week cycle to allow AMPK receptor sensitivity and NNMT enzyme activity to return to baseline

[DOI] [PMC free article] [PubMed] [Google Scholar] 36.Drmic D., Samara M., Vidovic T., Malekinusic D., Antunovic M., Vrdoljak B., Ruzman J., Perisa M.M., Pavlov K.H., Jeyakumar J., et al

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A neurorestorative changes the tissue, so the gain remains after the intervention stops