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The researchers commented that the downstream execution phase of programmed cell death may also be affected by AHK-Cu

Vitamin D aids in the production of antimicrobial peptides that help fight infections, while glutathione protects immune cells from oxidative damage

Antioxidant enzymes catalase, SOD, glutathione peroxidase, glutathione reductase, and thioredoxin act against the ROS

It's naturally produced by the body but can become depleted due to stress, illness, poor diet, or aging

F2-isoprostanes are ROS-mediated products of arachidonic acids and are very sensitive markers of the lipid peroxidation process (Dietrich-Muszalska and Kontek 2010)

The tightness of the BBB precludes the entrance of most pharmaceuticals into the brain via passive transcytosis, except for hydrophilic compounds which have a mass lower than 150 Da and highly hydrophobic compounds which have a mass lower than 400600 Da