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[DOI] [PubMed] [Google Scholar] 4.Cruciani RA, Dvorkin E, Homel P, Culliney B, Malamud S, Shaiova L, Fleishman S, Lapin J, Klein E, Lesage P, et al

In women with episodic migraines ( n = 92), ALA (300 mg twice daily) for 12 weeks significantly reduced migraine severity and frequency, and reduced serum lactate and vascular cell adhesion molecule-1, suggesting improvement in mitochondrial and endothelial function, respectively

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As anticipated, MG132 treatment led to a substantial increase in c-Myc protein levels, and the reduced amount of c-Myc protein in CPT1A-deficient cells was partially restored after MG132 treatment (Fig