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With the innovative ProTide technology and discovery of other nontoxic or less toxic pro-moieties, it would be wise to delve into testing safer metabolite based pro-moieties on previously potent or clinically approved compounds, as has been seen for TDF

They'll be much bigger and shaped differently than healthy ones

Even though preliminary results are promising, more research is needed to understand the mechanisms underlying DSIP and its broader medical applications

Synthetic neoantigens formed by proteasome-resistant modification of KRAS G12C peptides with covalent inhibitors are loaded onto HLAs as so-called haptenated peptides or p* (peptides still carrying the covalent inhibitor) and presented as p*MHCs on the cancer cell surface as homogeneously modified epitopes

BHRC Featured in GQ Magazine In a March 2026 GQ feature titled Its About to Be Hot Peptide Summer, BHRC Chief Innovation Officer Sanjiv Lal was interviewed alongside leading physicians and healthcare executives about the future of peptide regulation in the United States