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Revisiting immunological and clinical aspects of membranous nephropathy

A moderate increase in ROS levels can stimulate cell growth and proliferation, and allows for the normal physiological functions
10.1038/nature25158 Nature 89 VirgD.Dalmadi-KissB.VkeyK.DrahosL.KlebovichI.AntalI.et al (2020)

On his podcast, Andrew Huberman, MD, professor of neurobiology and ophthalmology at Stanford Universitys school of medicine, shared a potential, and slightly gory, origin story for BPC-157

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However, in GDH 1 knock-out mice (only humans express GDH 2) most functions, except the already mentioned reduced glutamate oxidation in cultured astrocytes, are remarkably intact (Frigerio et al., Table 2 Oxygen consumption rates as indications of kinetics of glutamate-dehydrogenase and aspartateglutamate transferase activities in non-synaptic mitochondria from the rat
