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Yehuda et al

Evidence remains largely preclinical, with growing interest in translational applications for aging, metabolic disorders, and neurodegeneration

Decreased levels of NAD + have been implicated in hypertension

Because the mechanism is appetite-based rather than metabolically suppressive, muscle preservation tends to be strong when paired with adequate protein and resistance training, which matters for sustaining results

74 The length that pericytes covering the CNS endothelium approaches 100%
