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Preclinical data highlight 3-5x efficacy gains, although clinical translation requires GSH gradient validation (143) (Figure 3)

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8 Therefore, MnSOD binds to both Mn 3+ and Fe 3+ , but is only active with Mn 3+/2+

Methylenetetrahydrofolate reductase (MTHFR) is associated with ovarian follicular activity

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