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In response to cold exposure, GDF15 secreted by BAT targets macrophages to suppress the expression of proinflammatory genes
As recently reviewed, OCTN2 is overexpressed in endometrial, ovarian, renal, pancreatic cancers and also in glioblastoma (GBM) even if neurons do not normally use fatty acids to derive energy (Juraszek and Nalecz, 2019)
[DOI] [PubMed] [Google Scholar] 52.Lan T, Wang Y, Chen Y, Qin W, Zhang J, Wang Z, et al
2019;14:e0225586
With respect to biological lipids, excess lipid intake, especially non-esterified saturated fatty acids (NEFA), leads to mitochondrial and endoplasmic reticulum (ER) stress
(2007) 137:830S-7S
