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Wnt-Surrogate was present at a 30 lower final concentration (16 pM)

Ascha et al., 2016)

The pipeline is open to repurposing existing drugs or drug combinations, novel small-molecules, and drugs based on emerging technologies like gene therapy, ASOs, and gene editing

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218 In glioblastoma, aspirin targets the SHH/GLI1 pathway to prevent GLI1 nuclear translocation, reprogram EMT, and enhance chemosensitivity to temozolomide (TMZ) by impairing DNA repair

As we refine our knowledge about microbiota-RT interactions, microbiome modulation strategies are poised to play a key role in personalized oncology radiation treatments
