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Sci Signal (2019) 12(589):eaaw3921

Provides intracellular antioxidant support

doi: 10.1016/0006-2952(60)90025-3 38 Perez-InestrosaE.SuauR.MontaezM

Serum iodide (I-) enters the follicular cell via a Na/I symporter against a concentration gradient, using the Na/K ATPase to generate the sodium gradient to drive iodide trapping. Thyroglobulin (TG) is exocytosed, and iodide is transported via the apical membrane anion transporter Pendrin , to the amorphous acellular colloid portion of the thyroid

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