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[DOI] [PMC free article] [PubMed] [Google Scholar] 24.Tian X., Thorne J.L., Moore J.B

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Although vitamin E exerts its antioxidant effect by preventing the oxidation of unsaturated fatty acids into hydroperoxides, exogenous antioxidants form the second line of defense against free radical damage in the body

Anti-IGF-1 receptor (IGF-1R) monoclonal antibodies (mAbs) were developed for clinical use in treating advanced stage cancers 22,23,24 , including Ganitumab, which remains under investigation as a combination therapy in clinical trials targeting Rhabdomyosarcoma (NCT03041701) and Ewing Sarcoma (NCT02306161), for which it recently received orphan drug status
