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doi: 10.1016/j.aspen.2017.03.015 101 SwartwoutM

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Yakubu Department of Clinical Pharmacy and Pharmacy Administration, University of Maiduguri, Nigeria

However, that study demonstrated that in early disease these cells are located in zone 3 of the hepatic acinus, distal to the zone 1 iron-laden hepatocytes, implying hepatic stellate cells are activated into collagen-producing myofibroblasts by soluble mediators released from iron-damaged hepatocytes rather than by iron per s [75, 85]

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