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Titration analysis of FLIP-G with GSH concentrations from nM to mM resulted in a sigmoid curve and affinity constants ( K d ) was found to be ~282 M (Fig

doi: 10.1097/MCO.0000000000000228

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However, the germline mutation of BAP1 is widely found in many cancers and makes tumor cells lose the vulnerability to ferroptosis, which is considered as an important susceptibility factor of hereditary cancers [101,102,103]

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