cysteine detection over homocysteine and glutathione in cells A colorimetric, ratiometric water-soluble fluorescent probe for simultaneously sensing and cysteine/homocysteine Dual-Channel fluorescent detection of Biothiols:

Given their enhanced stability and bioavailability, these analogues hold promise for therapeutic applications in conditions linked to oxidative stress, including neurodegenerative disorders, chronic inflammation, and metabolic diseases

Key Takeaway: The seven orders of magnitude more potent than BDNF claim comes from a single in vitro neurite outgrowth assay in McCoy et al

Hum Reprod Update 21:500516 Laschke MW, Schwender C, Scheuer C, Vollmar B, Menger MD (2008) Epigallocatechin-3-gallate inhibits estrogen-induced activation of endometrial cells in vitro and causes regression of endometriotic lesions in vivo

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doi:10.1111/j.1471-4159.2006.03693.x

Eligible patients received NSI-189 or placebo for 28 days in an inpatient setting with assessments for safety, pharmacokinetics (PK) and efficacy