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To avoid a potential risk of hypercobalaminemia or possible health risks of high-dose dietary supplements, an annual blood test is recommended, after which targeted substitution can be performed

This often manifests as slight changes in stubborn fat areas, increased definition in certain areas, or measurable changes on body composition assessments

Although, further research is needed to support the claim

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In simple terms, the observed cosmetic changes (fewer wrinkles, tighter skin, stronger hair) match what GHK-Cus biology would predict