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Clinically, this manifests as peripheral neuropathy, characterized by numbness, painful tingling, burning sensations in the extremities, and eventual loss of motor function

Given the rarity of application of these techniques, long-term effects in offspring generated via MRT are not known and additional investigation is necessary to further define and classify long-term effects and implications (Farnezi et al., 2020)

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In the meanwhile, they achieve the uptake of essential nutrients and clearance of exogenous substances via carrier proteins (e.g., glucose transporter, GLUT) and efflux pumps (e.g., P-glycoprotein, P-gP) on the cell membrane, realizing regulation of transmembrane transport processes

An innovative NRF2 nano-modulator induces lung cancer ferroptosis and elicits an immunostimulatory tumor microenvironment

doi: 10.3390/cancers12010138