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l carnitine and ammonia levels Quantitative systems pharmacology Model to characterize valproic acid-induced hyperammonemia the effect of L-carnitine supplementation Reversible weakness and encephalopathy while

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It is a promising preclinical anti-tuberculosis drug candidate and has been studied in phase 2b/3 clinical trials [24]

l carnitine and ammonia levels Quantitative systems pharmacology Model to characterize valproic acid-induced hyperammonemia the effect of L-carnitine supplementation Reversible weakness and encephalopathy while

doi: 10.1111/jog.12177 99 JamilianMForoozanfardFMirhosseiniNKavossianEAghadavodEBahmaniFet al

l carnitine and ammonia levels Quantitative systems pharmacology Model to characterize valproic acid-induced hyperammonemia the effect of L-carnitine supplementation Reversible weakness and encephalopathy while

Side effects are rare and usually mild, such as temporary muscle weakness or localized swelling

l carnitine and ammonia levels Quantitative systems pharmacology Model to characterize valproic acid-induced hyperammonemia the effect of L-carnitine supplementation Reversible weakness and encephalopathy while

J Clin Med 13:1933 Chang CC, Hsu HF, Huang KH, Wu JM, Kuo SM, Ling XH, Houng JY (2014) Anti-proliferative effects of Siegesbeckia orientalis ethanol extract on human endometrial RL-95 cancer cells

l carnitine and ammonia levels Quantitative systems pharmacology Model to characterize valproic acid-induced hyperammonemia the effect of L-carnitine supplementation Reversible weakness and encephalopathy while

Precise parameters and relatively comprehensive models are essential if bystander effects are to be accurately described

l carnitine and ammonia levels Quantitative systems pharmacology Model to characterize valproic acid-induced hyperammonemia the effect of L-carnitine supplementation Reversible weakness and encephalopathy while

DISCLOSURES The authors declare no conflicts of interest

l carnitine and ammonia levels Quantitative systems pharmacology Model to characterize valproic acid-induced hyperammonemia the effect of L-carnitine supplementation Reversible weakness and encephalopathy while

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