l carnitine and ammonia levels Quantitative systems pharmacology Model to characterize valproic acid-induced hyperammonemia the effect of L-carnitine supplementation Reversible weakness and encephalopathy while
Description
It is a promising preclinical anti-tuberculosis drug candidate and has been studied in phase 2b/3 clinical trials [24]

doi: 10.1111/jog.12177 99 JamilianMForoozanfardFMirhosseiniNKavossianEAghadavodEBahmaniFet al

Side effects are rare and usually mild, such as temporary muscle weakness or localized swelling

J Clin Med 13:1933 Chang CC, Hsu HF, Huang KH, Wu JM, Kuo SM, Ling XH, Houng JY (2014) Anti-proliferative effects of Siegesbeckia orientalis ethanol extract on human endometrial RL-95 cancer cells

Precise parameters and relatively comprehensive models are essential if bystander effects are to be accurately described
DISCLOSURES The authors declare no conflicts of interest
