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Another novel approach that has been tested in mouse models of brain-metastatic breast cancer and showed some promising results, is the inhibition of the adhesion of cancer cells to pre-existing blood vessels to block vessel co-option through inhibition of L1 Cell Adhesion Molecule (L1CAM) or the cell adhesion receptor 1 integrin [115]

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Different hormones (e.g

Generalized application of NERNST in biochemical, biotech and medical research will open up novel perspectives to study the contribution of NADP(H) in such fundamental biological processes as embryogenesis, aging, inflammation and cell death, tissue regeneration and disease responses