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Can tissue-specific RAGE inhibition strategies overcome the limitations of systemic RAGE antagonists to effectively delay ovarian aging while preserving physiological RAGE functions in other organs

Although a Consensus Conference in 1992 recommended that the term dysplastic nevus no longer be used, the histologic diagnosis continues to present a therapeutic quandary for dermatologists and other physicians, and there remains significant variation in clinical management

Both modalities did not demonstrate a significant clinical nor dermoscopic response

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