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Vaccines with a high theoretical risk of inducing pathologic ADE or ERD include inactivated viral vaccines, which may contain non-neutralizing antigen targets and/or the S protein in non-neutralizing conformations, providing a multitude of non-protective targets for antibodies that could drive additional inflammation via the well-described mechanisms observed for other respiratory pathogens

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Also, glutamate excitotoxicity, itself, forms fragmented mitochondria, contributing to oxidative stress through the dysfunctional mitochondria (80)

It believes they suit dynamic uses thanks to exhibiting favorable therapeutic effectiveness

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Dysregulation of NMDAR signalingwhether through altered receptor expression, impaired trafficking, or disrupted subunit compositionhas been implicated in a broad range of neurological and psychiatric disorders