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When recruited, it becomes oligomerized and is transported to mitochondria where it interacts with protein adaptors, such as the mitochondrial fission factor (Mff), the mitochondrial fission protein 1 (Fis1), the mitochondrial dynamics protein 49 (MiD49/MIEF2), and the mitochondrial dynamics protein 51 (MiD51/MIEF1) [315]

Finally, from the initial conception this study aimed to examine safety and compliance within a small cohort and was not designed to completely accommodate the genetic and phenotypic heterogeneity of children with NF1 and was not powered toward functional outcomes

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Mol Genet Metab 100(Suppl 1):S53S58 Braissant O (2012) Creatine and guanidinoacetate transport at bloodbrain and blood-cerebrospinal fluid barriers

Although L-Carnitine is generally considered a natural and safe supplement, there are certain situations where extra caution is advised