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Thiamine vitamin B1 injection for deficiency symptoms

R., McCaddon, A., Ahmadi, K

As all cells in the body require cobalamin for single carbon metabolism, it has been hypothesized that cobalamin deficiency may actually contribute to the clinical signs and manifestations of gastrointestinal disease in some patients

Deficiency could potentially lead to dysregulated local immune responses in the oral mucosa, possibly triggering or perpetuating ulcerative lesions

Macrophages switch between repair-promoting phenotypes and those that extend inflammation

Phase II typically funds up to $1,000,000 to $1,500,000 for 24-36 months to continue the R&D effort from the completed Phase I project and work towards a prototype demonstration