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2 Triggers of astrocyte activation in TBI Astrocyte activation in the acute phase following TBI is a complex process initiated by multiple interrelated mechanisms

Thus, it only affects those activated phagocytes that are producing the hydrogen peroxide necessary for peroxidase activity (Simons et al., 1990


Following an acute toxic ingestion, the clinical course typically occurs in stages, starting with mild, nonspecific symptoms (eg, nausea, malaise) followed by right upper quadrant abdominal pain, rising aminotransferases, and, in severe cases, fulminant liver failure within a matter of days

[DOI] [PMC free article] [PubMed] [Google Scholar] 147.Ma G, et al

In addition, transcellular flux is also restricted, as these ECs show extremely low transcytotic activity (Coomber and Stewart, 1985)
