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Research shows that low B12 levels are associated with increased body fat, disrupted fat processing and insulin resistance, highlighting its role in maintaining metabolic balance

B12 is also involved in cellular metabolic processes such as DNA synthesis and regulation, synthesis of fatty acids and energy production

Prevent twitches with good hydration and sleep, regular exercise, and a balanced diet that provides plenty of calcium, potassium, and magnesium

Vitamin D, magnesium, and iron deficiencies are frequently documented in patients on long-term GLP-1 therapy

If you suspect you have B12 deficiency then its probably a good idea to run a trial of B12 supplementation simply because taking B12 is safe as long as your kidneys are functioning

Absorption problems Even with adequate intake, absorption can be reduced by: Certain gastrointestinal conditions affecting the stomach or small intestine Some medications Age-related reduction in stomach acid (which can affect absorption) Autoimmune gastritis (often historically referred to as pernicious anaemia) This is a well-recognised cause of B12 deficiency and may require ongoing management