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Aging cell, doi:10.1111/acel.12950 (2019 (in press))

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Why experts are watching: Chronic illness is driving demand for earlier, more precise biomarkers and epigenetic clocks are emerging as one of the strongest predictors of healthspan

The mTOR protein kinase inhibitors mTOR, a serine/threonine protein kinase, is ubiquitously expressed in cells, and enhanced activity of the mTOR pathway is frequently observed in malignant cells, including RCC

Focal adhesion kinase (FAK) and paxillin are instrumental mechanotransduction proteins that regulate how cells attach to the extracellular matrix and migrate across it