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doi: 10.1021/acsomega.1c07218

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Liu HW, Chan YC, Wang MF, Wei CC, Chang SJ

Not all medications and nutrients are small enough to get absorbed or need breakdown via gastric enzymes for activation for the sublingual route, but whenever possible there is a benefit to using this route as it bypasses potential damage/absorption issues in the GI tract

It is worth noting that the short half-life does not mean the benefits are equally short-lived

Combining it with PRP (platelet-rich plasma) amplifies results through the vampire facial technique
