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Each variable was scored for each sample slide, and we used a common scoring system where [0] = no alteration, [1] = mild changes, [2] = moderate changes, and [3] = severe changes (Kalantar et al., 2019b
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While each of these domains has been extensively discussed individually, it is their convergence that underlies the shared pathophysiological mechanisms observed in clinical and molecular studies
ATP- and glutathione-dependent transport of chemotherapeutic drugs by the multidrug resistance protein MRP1
Other causes can include cancer, toxins and infection
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